Several clinical studies have shown the efficacy of Orlistat in facilitating weight loss. 

Orlistat when combined with lifestyle interventions resulted in 3 kg more weight loss than did placebo after 12 months. 

Weight loss was found to be maintained with up to 24 to 36 months of treatment with Orlistat.

In addition, Orlistat was found to improve blood pressure and cholesterol levels. 

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